3T Strada's are now running 12 Speed SRAM wireless ETAP AXS. They're exclusively for purchase at Bicicletta online and in store
The Strada Due runs 2x electronic drivetrains from Shimano, Campagnolo & SRAM. And you still get the 30mm tire fit & aerodynamics designed around such tires.
The biggest factor in road bike comfort are the tires; they provide more compliance than any other part of the bike. Wider tires are better at reducing shocks from cracks, curbs, cobbles and potholes, which is why they are the norm at Paris- Roubaix. Wider tires also have lower rolling resistance, because their shorter contact patch requires less bending by the casing.